Listar Investigación y Desarrollo por autor "Cuendias, Patricia"
Mostrando ítems 1-9 de 9
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Article
Acid-Sensing Ion Channels’ Immunoreactivity in Nerve Profiles and Glomus Cells of the Human Carotid Body (2024)
Martínez-Barbero, Graciela; García-Mesa, Yolanda; Cobo, Ramón; Cuendias, Patricia; Martín-Biedma, Benjamín; García-Suárez, Olivia; Feito, Jorge; Cobo, Teresa; Vega, José A. (Multidisciplinary Digital Publishing Institute (MDPI), 2023)The carotid body is a major peripheral chemoreceptor that senses changes in arterial blood oxygen, carbon dioxide, and pH, which is important for the regulation of breathing and cardiovascular function. The mechanisms by ... -
Article
Differences between finger and toe Meissner corpuscles: Searching for the optimal place to analyze meissner corpuscles in cutaneous biopsy (2023)
Cuendias, Patricia; del Rio, Rebeca; García-Suárez, Olivia; Cobo, Ramón; Aragona, Marialuisa; Feito, Jorge; Martín-Biedma, Benjamín; Vega, José A.; García-Mesa, Yolanda (Elsevier GmbH, 2023-03)Background: Skin biopsy is a minimally invasive and repeatable technique, applicable in any part of the body that can allows for diagnosis and control of treatments, but to analyze Meissner corpuscles biopsy of glabrous ... -
Article
Exploring somatosensory innervation of the human lip: A focus on the vermilion (2024)
Martín-Cruces, José; Martín-Biedma, Benjamín; García-Mesa, Yolanda; Cuendias, Patricia; Gaite, Juan J.; García-Suárez, Olivia; Cobo, Juan L.; Vega, José A. (Elsevier GmbH, 2023)Background: The lips are a vital component of the face and are densely innervated to perform various functions. The lip edges are covered with mucocutaneous tissue called vermilion which is particularly receptive to touch ... -
Article
Immunohistochemical detection of PIEZO1 and PIEZO2 in human digital Meissner´s corpuscles (2024)
García-Mesa, Yolanda; Cuendias, Patricia; Alonso-Guervós, Marta; García-Piqueras, Jorge; Martín-Biedma, Benjamín; Cobo, Teresa; García-Suárez, Olivia; Vega, José A. (Elsevier GmbH, 2024)Background: The cutaneous end organ complexes or cutaneous sensory corpuscles are specialized sensory organs associated to low-threshold mechanoreceptors. Mechano-gated proteins forming a part of ion channels have been ... -
Article
Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament (2024)
Gaite, Juan J.; Solé-Magdalena, Antonio; García-Mesa, Yolanda; Cuendias, Patricia; Martin-Cruces, José; García-Suárez, Olivia; Cobo, Teresa; Vega, José A.; Martín-Biedma, Benjamín (John Wiley and Sons Inc, 2023)PIEZO1 and PIEZO2 are essential components of mechanogated ion channels, which are required for mechanotransduction and biological processes associated with mechanical stimuli. There is evidence for the presence of PIEZO1 ... -
Article
Proprioceptive innervation of the human lips (2024)
Martín-Cruces, José; Cuendias, Patricia; García-Mesa, Yolanda; Cobo, Juan L.; García-Suárez, Olivia; Gaite, Juan J.; Vega, José A.; Martín-Biedma, Benjamín (John Wiley and Sons Inc, 2024)The objective of this study was to analyze the proprioceptive innervation of human lips, especially of the orbicularis oris muscle, since it is classically accepted that facial muscles lack typical proprioceptors, that is, ... -
Article
Sensory innervation of the human shoulder joints in healthy and in chronic pain shoulder syndromes (2024)
Martínez-Gago, Abel; García-Mesa, Yolanda; Cuendias, Patricia; Martín-Cruces, José; Abellán, Juan F.; García-Suárez, Olivia; Vega, José A. (Elsevier GmbH, 2024)Background: Afferent innervation of shoulder joints plays a fundamental role in nociception and mechanoception and its alteration result in shoulder´s disease that course with pain and functional disability. Methods: Joints ... -
Article
Synaptophysin is a selective marker for axons in human cutaneous end organ complexes (2024)
García-Mesa, Yolanda; García-Piqueras, Jorge; Cuendias, Patricia; Cobo, Ramón; Martín-Cruces, José; Feito, Jorge; García-Suarez, Olivia; Biedma, Benjamín Martín; Vega, J.A. (Elsevier GmbH, 2022)Background: Small clear synaptic-like vesicles fill axon terminals of mechanoreceptors. Their functional significance is controversial and probably includes release of neurotransmitters from afferent axon terminals. ... -
Article
The acquisition of mechanoreceptive competence by human digital Merkel cells and sensory corpuscles during development: An immunohistochemical study of PIEZO2 (2022)
García-Mesa, Yolanda; Feito, Jorge; Cuendias, Patricia; García-Piqueras, Jorge; Germanà, Antonino; García-Suárez, Olivia; Martín-Biedma, Benjamín; Vega, José A. (Elsevier GmbH, 2022-08)Background: PIEZO2 is a transmembrane protein forming part of an ion channel required for mechanotransduction. In humans, PIEZO2 is present in axon terminals of adult Meissner and Pacinian corpuscles, as well as Merkel ...