• Article

      Dexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice (2021) 

      Ettcheto, Miren; Sánchez-López, Elena; Cano, Amanda; Carrasco, Marina; Herrera, Katherine; Manzine, Patricia Regina; Espinosa-Jiménez, Triana; Busquets, Oriol; Verdaguer, Ester; Olloquequi, Jordi; ... (BioMed Central Ltd, 2021-12)
      Background: Several studies stablished a relationship between metabolic disturbances and Alzheimer´s disease (AD) where inflammation plays a pivotal role. However, mechanisms involved still remain unclear. In the present ...
    • Article

      Impact of New Drugs for Therapeutic Intervention in Alzheimer’s Disease (2024) 

      Olloquequi, Jordi; Ettcheto, Miren; Cano, Amanda; Sanchez-López, Elena; Carrasco, Marina; Espinosa, Triana; Beas-Zarate, Carlos; Gudiño-Cabrera, Graciela; Ureña-Guerrero, Monica E.; Verdaguer, Ester; ... (Bioscience Research Institute, 2022)
      The increases in population ageing and growth are leading to a boosting in the number of people living with dementia, Alzheimer’s disease (AD) being the most common cause. In spite of decades of intensive research, no cure ...
    • Article

      Protein tyrosine phosphatase 1B (PTP1B) as a potential therapeutic target for neurological disorders (2024) 

      Olloquequi, Jordi; Cano, Amanda; Sanchez-López, Elena; Carrasco, Marina; Verdaguer, Ester; Fortuna, Ana; Folch, Jaume; Bulló, Mònica; Auladell, Carme; Camins, Antoni; ... (Elsevier Masson s.r.l., 2022)
      Protein tyrosine phosphatase 1B (PTP1B) is a typical member of the PTP family, considered a direct negative regulator of several receptor and receptor-associated tyrosine kinases. This widely localized enzyme has been ...