Listar Investigación y Desarrollo por autor "Balmazabal, Javiera"
Mostrando ítems 1-3 de 3
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Article
Astroglial hemichannels and pannexons: The hidden link between maternal inflammation and neurological disorders (2021)
Prieto-Villalobos, Juan; Alvear, Tanhia F.; Liberona, Andrés; Lucero, Claudia M.J.; Martínez-Araya, Claudio J.; Balmazabal, Javiera; Inostroza, Carla A.; Ramírez, Gigliola; Gómez, Gonzalo I.; Orellana, Juan Andrés (MDPI, 2021-09-01)Maternal inflammation during pregnancy causes later-in-life alterations of the offspring’s brain structure and function. These abnormalities increase the risk of developing several psychiatric and neurological disorders, ... -
Article
Hypertensive Nephropathy: Unveiling the Possible Involvement of Hemichannels and Pannexons (2024)
Lucero, Claudia M.; Prieto-Villalobos, Juan; Marambio-Ruiz, Lucas; Balmazabal, Javiera; Alvear, Tanhia F.; Vega, Matías; Barra, Paola; Retamal, Mauricio A.; Orellana, Juan A.; Gómez, Gonzalo I. (MDPI, 2022)Hypertension is one of the most common risk factors for developing chronic cardiovascular diseases, including hypertensive nephropathy. Within the glomerulus, hypertension causes damage and activation of mesangial cells ... -
Article
TNF-α Plus IL-1β Induces Opposite Regulation of Cx43 Hemichannels and Gap Junctions in Mesangial Cells through a RhoA/ROCK-Dependent Pathway (2024)
Lucero, Claudia M.; Marambio-Ruiz, Lucas; Balmazabal, Javiera; Prieto-Villalobos, Juan; León, Marcelo; Fernández, Paola; Orellana, Juan A.; Velarde, Victoria; Sáez, Juan C.; Gómez, Gonzalo I. (MDPI, 2022)Connexin 43 (Cx43) is expressed in kidney tissue where it forms hemichannels and gap junction channels. However, the possible functional relationship between these membrane channels and their role in damaged renal cells ...