Listar Investigación y Desarrollo por autor "Amador, Cristián A."

Mostrando ítems 1-5 de 5

    • Article

      Neutrophil gelatinase–associated lipocalin as an immunomodulator in endocrine hypertension (2024) 

      Araos, Patricio; Amador, Cristián A. (Frontiers Media S.A., 2022)
      In recent studies, primary aldosteronism (PA) has been reported as the most common etiology for secondary hypertension of endocrine origin, accounting for approximately 10% of cases. In PA, excess aldosterone production ...
    • Article

      Oxidized albumin as a mediator of kidney disease (2021) 

      Figueroa, Stefanny M.; Araos, Patricio; Reyes, Javier; Gravez, Basile; Barrera-Chimal, Jonatan; Amador, Cristián A. (MDPI AG, 2021-03)
      Renal diseases are a global health concern, and nearly 24% of kidney disease patients are overweight or obese. Particularly, increased body mass index has been correlated with oxidative stress and urinary albumin excretion ...
    • Article

      The advantages of polymeric hydrogels in calcineurin inhibitor delivery (2020) 

      Sandoval-Yañez, Claudia; Escobar, Leslie; Amador, Cristián A. (MDPI AG, 2020-10-22)
      In recent years, polymeric hydrogels (PolyHy) have been extensively explored for their applications in biomedicine as biosensors, in tissue engineering, diagnostic processes, and drug release. The physical and chemical ...
    • Article

      The Mineralocorticoid Receptor on Smooth Muscle Cells Promotes Tacrolimus-Induced Renal Injury in Mice (2024) 

      Figueroa, Stefanny M.; Bertocchio, Jean-Philippe; Nakamura, Toshifumi; El-Moghrabi, Soumaya; Jaisser, Frédéric; Amador, Cristián A. (MDPI, 2023)
      Tacrolimus (Tac) is a calcineurin inhibitor commonly used as an immunosuppressor after solid organ transplantation. However, Tac may induce hypertension, nephrotoxicity, and an increase in aldosterone levels. The activation ...
    • Article

      The role of neutrophils in hypertension (2020) 

      Araos, Patricio; Figueroa, Stefanny; Amador, Cristián A. (MDPI AG, 2020-11-02)
      It is well accepted that the immune system and some cells from adaptive and innate immunity are necessary for the initiation/perpetuation of arterial hypertension (AH). However, whether neutrophils are part of this group ...