• Article

      Astroglial hemichannels and pannexons: The hidden link between maternal inflammation and neurological disorders (2021) 

      Prieto-Villalobos, Juan; Alvear, Tanhia F.; Liberona, Andrés; Lucero, Claudia M.J.; Martínez-Araya, Claudio J.; Balmazabal, Javiera; Inostroza, Carla A.; Ramírez, Gigliola; Gómez, Gonzalo I.; Orellana, Juan Andrés (MDPI, 2021-09-01)
      Maternal inflammation during pregnancy causes later-in-life alterations of the offspring’s brain structure and function. These abnormalities increase the risk of developing several psychiatric and neurological disorders, ...
    • Article

      Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage (2024) 

      Gómez, Gonzalo I.; Alvear, Tanhia F.; Roa, Daniela A.; Farias-Pasten, Arantza; Vergara, Sergio A.; Mellado, Luis A.; Martinez-Araya, Claudio J.; Prieto-Villalobos, Juan; García-Rodríguez, Claudia; Sánchez, Natalia; ... (BioMed Central Ltd, 2024)
      Background: Alcohol, a widely abused drug, significantly diminishes life quality, causing chronic diseases and psychiatric issues, with severe health, societal, and economic repercussions. Previously, we demonstrated that ...
    • Article

      Hypertensive Nephropathy: Unveiling the Possible Involvement of Hemichannels and Pannexons (2024) 

      Lucero, Claudia M.; Prieto-Villalobos, Juan; Marambio-Ruiz, Lucas; Balmazabal, Javiera; Alvear, Tanhia F.; Vega, Matías; Barra, Paola; Retamal, Mauricio A.; Orellana, Juan A.; Gómez, Gonzalo I. (MDPI, 2022)
      Hypertension is one of the most common risk factors for developing chronic cardiovascular diseases, including hypertensive nephropathy. Within the glomerulus, hypertension causes damage and activation of mesangial cells ...