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Article
Targeting CCR3 with antagonist SB 328437 sensitizes 5‑fluorouracil‑resistant gastric cancer cells: Experimental evidence and computational insights (2024)
(Spandidos Publications, 2024)Gastric cancer (GC) ranks fifth globally in cancer diag‑ noses and third for cancer‑related deaths. Chemotherapy with 5‑fluorouracil (5‑FU), a primary treatment, faces challenges due to the development of chemoresistance. ... -
Article
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis (2020)
(Elsevier Masson s.r.l., 2020-10-28)Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no known cure. Aggregates of the nuclear protein TDP-43 have been recognized as a hallmark of proteinopathy in both familial and sporadic cases ... -
Article
Targeting the nicotinic acetylcholine receptors (nAChRs) in astrocytes as a potential therapeutic target in Parkinson’s disease (2020)
(Bentham Science Publishers, 2016) -
Article
Targeting α -(1,4)-glucosidase in diabetes mellitus type 2: The role of new synthetic coumarins as potent inhibitors (2020)
(Bentham Science Publishers B.V., 2018) -
Review
TASK Channels Pharmacology: New Challenges in Drug Design (2020)
(American Chemical Society, 2019) -
Article
Task planning for sports learning by physical education teachers in the pre-service phase (2020)
(Public Library of Science, 2019) -
Article
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Article
Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D (2021)
(Frontiers Media S.A., 2021-02-10)Aging is an irreversible process and the primary risk factor for the development of neurodegenerative diseases, such as Alzheimer’s disease (AD). Mitochondrial impairment is a process that generates oxidative damage and ... -
Article
Taxonomic Reframe of Some Species of the Genera Haloferax and Halobellus (2024)
(Springer, 2024)Haloferax and Halobellus are the representatives of the family Haloferacaceae and they are dominant in hypersaline ecosystems. Some Haloferax and Halobellus species exhibit a close evolutionary relationship. Genomic, ... -
Article
TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: Facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline (2021)
(Royal Society of Chemistry, 2021-04-15)Multi-reactive centered reagents are beneficial in chemical synthesis due to their advantage of minimal material utilization and formation of less by-products. Trichloroisocyanuric acid (TCCA), a reagent with three reactive ... -
Article
TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy (2022)
(American Chemical Society, 2021)Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease without any effective treatment. Protein TDP-43 is a pathological hallmark of ALS in both sporadic and familiar patients. Post-translational modifications ... -
Article
Teacher competences in online education in time of COVID-19: Public Universities of Honduras (2020)
(Universidad del Zulia, 2020)It is the higher education center that governs the task of knowledge management and promotion, in order to develop professionals, which is why the work of the teacher is prevalent in their training. This article analyzes ... -
Article
Teacher identity of educators working in alternative school settings: Montessori and Waldorf-Steiner (2024)
(Emerson de Pietri, 2023)This article is a qualitative research about the perspective of teachers working in Montessori and Waldorf-Steiner schools, in the Chilean educational context. The objective is to analyze the teacher identity specifically ... -
Article
Teacher technostress in the chilean school system (2020)
(MDPI AG, 2020) -
Article
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Article
Teachers Perceptions of the Construction of Mathematical Concepts in Everyday Contexts (2021)
(Lutheran University of Brazil, 2021-05)Background: As it is important to link the disciplines to real contexts, it is necessary to propose teaching-learning strategies based on diverse situations, inside or outside the mathematical field. This study considers ... -
Article
Teachers’ perceptions of barriers and facilitators of the school environment for physical activity in schoolchildren: a qualitative study (2022)
(Routledge, 2022)A qualitative study based on grounded theory was carried out to analyse the facilitators and barriers of the school environment for physical activity (PA) perceived by teachers at schools in Cuenca and Ciudad Real (Castilla ... -
Article
Teachers’ visions on the participation of migrant families in the Chilean school (2021)
(Universidad Autonoma de Madrid, 2021-06)The study aims to describe the teachers’ views on the participation of migrant families in the school, in terms of how it establishes linkage mechanisms with parents and how they participate in the school process of their ... -
Article
Teaching and learning law and artificial intelligence in Chile: On the minor in Artificial Intelligence and Law at the Universidad Autónoma de Chile (2022)
(Universidad de Chile, 2021)The paper addresses the penetration of new technologies in the Chilean legal profession, in order to explain the curricular innovation of the minor in artificial intelligence and law (IA+D), according to its learning ... -
Article
Teaching ethics in the university through multicultural online dialogue (2020)
(Grupo Communicar Ediciones, 2016)