Listar Artículos científicos por autor "Prieto-Villalobos, Juan"
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Astroglial hemichannels and pannexons: The hidden link between maternal inflammation and neurological disorders (2021)
Prieto-Villalobos, Juan; Alvear, Tanhia F.; Liberona, Andrés; Lucero, Claudia M.J.; Martínez-Araya, Claudio J.; Balmazabal, Javiera; Inostroza, Carla A.; Ramírez, Gigliola; Gómez, Gonzalo I.; Orellana, Juan Andrés (MDPI, 2021-09-01)Maternal inflammation during pregnancy causes later-in-life alterations of the offspring’s brain structure and function. These abnormalities increase the risk of developing several psychiatric and neurological disorders, ... -
Article
Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage (2024)
Gómez, Gonzalo I.; Alvear, Tanhia F.; Roa, Daniela A.; Farias-Pasten, Arantza; Vergara, Sergio A.; Mellado, Luis A.; Martinez-Araya, Claudio J.; Prieto-Villalobos, Juan; García-Rodríguez, Claudia; Sánchez, Natalia; ... (BioMed Central Ltd, 2024)Background: Alcohol, a widely abused drug, significantly diminishes life quality, causing chronic diseases and psychiatric issues, with severe health, societal, and economic repercussions. Previously, we demonstrated that ... -
Article
Hypertensive Nephropathy: Unveiling the Possible Involvement of Hemichannels and Pannexons (2024)
Lucero, Claudia M.; Prieto-Villalobos, Juan; Marambio-Ruiz, Lucas; Balmazabal, Javiera; Alvear, Tanhia F.; Vega, Matías; Barra, Paola; Retamal, Mauricio A.; Orellana, Juan A.; Gómez, Gonzalo I. (MDPI, 2022)Hypertension is one of the most common risk factors for developing chronic cardiovascular diseases, including hypertensive nephropathy. Within the glomerulus, hypertension causes damage and activation of mesangial cells ... -
Article
SARS-CoV-2 spike protein S1 activates Cx43 hemichannels and disturbs intracellular Ca2+ dynamics (2024)
Prieto-Villalobos, Juan; Lucero, Claudia M.; Rovegno, Maximiliano; Gómez, Gonzalo I.; Retamal, Mauricio A.; Orellana, Juan A. (BioMed Central Ltd, 2023)Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the ongoing coronavirus disease 2019 (COVID-19). An aspect of high uncertainty is whether the SARS-CoV-2 per se or the systemic inflammation ... -
Article
TNF-α Plus IL-1β Induces Opposite Regulation of Cx43 Hemichannels and Gap Junctions in Mesangial Cells through a RhoA/ROCK-Dependent Pathway (2024)
Lucero, Claudia M.; Marambio-Ruiz, Lucas; Balmazabal, Javiera; Prieto-Villalobos, Juan; León, Marcelo; Fernández, Paola; Orellana, Juan A.; Velarde, Victoria; Sáez, Juan C.; Gómez, Gonzalo I. (MDPI, 2022)Connexin 43 (Cx43) is expressed in kidney tissue where it forms hemichannels and gap junction channels. However, the possible functional relationship between these membrane channels and their role in damaged renal cells ...