Listar Artículos científicos por autor "Platzk, Magdalena"
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Article
5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a new family of task-3 channel blockers: A pharmacophore-based regioselective synthesis (2021)
Ramírez, David; Mejiá-Gutiérrez, Melissa; Insuasty O, Braulio; Rinné, Susanne; Kiper, Aytuğ K.; Platzk, Magdalena; Müller, Thomas; Decher, Niels; Quiroga, Jairo; De la Torre, Pedro; ... (MDPI AG, 2021-07-01)TASK channels belong to the two-pore-domain potassium (K2P) channels subfamily. These channels modulate cellular excitability, input resistance, and response to synaptic stimulation. TASK-channel inhibition led to membrane ...