Listar Artículos científicos por autor "Pérez, Concepción"
Mostrando ítems 1-2 de 2
-
Article
From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein-Templated Synthesis (2021)
Nozal, Vanesa; García-Rubia, Alfonso; Cuevas, Eva P.; Pérez, Concepción; Tosat-Bitrián, Carlota; Bartolomé, Fernando; Carro, Eva M.; Ramírez, David; Palomo, Valle; Martínez, Ana (John Wiley and Sons Inc, 2021)Multitarget directed ligands (MTDLs) are arising as promising tools to tackle complex diseases. The main goal of this work is to create powerful modulating agents for neurodegenerative disorders. To achieve this aim, we ... -
Article
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis (2020)
Rojas-Prats, Elisa; Martínez-González, Loreto; Gonzalo-Consuegra, Claudia; Liachko, Nicole F.; Pérez, Concepción; Ramírez, David; Kraemer, Brian C.; Martín-Requero, Ángeles; Perez, Daniel I.; Gil, Carmen; ... (Elsevier Masson s.r.l., 2020-10-28)Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no known cure. Aggregates of the nuclear protein TDP-43 have been recognized as a hallmark of proteinopathy in both familial and sporadic cases ...