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A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet (2024)
(BioMed Central Ltd, 2023)
Background: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the global burden of AD and the advances made in AD drug research and development, the cure of the disease remains elusive, since ...
8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies (2024)
(Elsevier Masson s.r.l., 2023)
Psychiatric and neurological disorders affect millions of people worldwide. Currently available treatments may help to improve symptoms, but they cannot cure the diseases. Therefore, there is an urgent need for potent and ...
Ethical conflicts among physicians and nurses during the COVID-19 pandemic: A qualitative study (2024)
(John Wiley and Sons Inc, 2023)
Rationale, Aims and Objectives: The healthcare system and professionals working in the sector have experienced a high caseload during the coronavirus disease 2019 (COVID-19) pandemic. This has increased the potential for ...
Changes in the Mechanical Properties of the Horizontal Force-Velocity Profile during a Repeated Sprint Test in Professional Soccer Players (2024)
(MDPI, 2023)
The objective was to analyze the changes in the horizontal force-velocity profile (HFVP) during the execution of repeated sprinting. Methods: Seventeen first-division Chilean soccer players completed a repeated sprint ...
SARS-CoV-2 spike protein S1 activates Cx43 hemichannels and disturbs intracellular Ca2+ dynamics (2024)
(BioMed Central Ltd, 2023)
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the ongoing coronavirus disease 2019 (COVID-19). An aspect of high uncertainty is whether the SARS-CoV-2 per se or the systemic inflammation ...
Learning Experiences of Future Healthcare Support Workers Enrolled in a Dual Mode Vocational Training Programme (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Background: With life expectancy increasing, there is a growing need to train healthcare support workers who provide care for dependent people in healthcare centres and at home. This qualitative study, based on Gadamer’s ...
The effect of exercise on suicidal ideation and behaviors: A systematic review and meta-analysis of randomized controlled trials (2024)
(Elsevier B.V., 2023)
Background: Although exercise may positively impact those with mental or other medical illnesses, there is a lack of understanding on how it influences suicidal ideation or risk. Methods: We conducted a PRISMA 2020-compliant ...
Use of Chitosan-Based Polyelectrolyte Complexes for Its Potential Application in Active Food Packaging: A Review of Recent Literature (2024)
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
The current challenges in the food packaging field are, on one side, replacing plastic from non-renewable sources with biopolymers and, on the other hand, generating a packaging material with attractive properties for the ...
Editorial: Towards a basic standard methodology for international research in psychology (2024)
(Frontiers Media S.A., 2023)
[No abstract available]
Hidden demographic impacts of fishing and environmental drivers of fecundity in a sea turtle population (2024)
(John Wiley and Sons Inc, 2023)
Fisheries bycatch is a critical threat to sea turtle populations worldwide, particularly because turtles are vulnerable to multiple gear types. The Canary Current is an intensely fished region, yet there has been no ...