ListarProducción Científica por tema "PIEZO2"

Mostrando ítems 1-8 de 8

    • Article

      Exploring somatosensory innervation of the human lip: A focus on the vermilion (2024) 

      Martín-Cruces, José; Martín-Biedma, Benjamín; García-Mesa, Yolanda; Cuendias, Patricia; Gaite, Juan J.; García-Suárez, Olivia; Cobo, Juan L.; Vega, José A. (Elsevier GmbH, 2023)
      Background: The lips are a vital component of the face and are densely innervated to perform various functions. The lip edges are covered with mucocutaneous tissue called vermilion which is particularly receptive to touch ...
    • Article

      Glans clitoris innervation: PIEZO2 and sexual mechanosensitivity (2020) 

      García-Mesa, Yolanda; Cárcaba, Lucía; Coronado, César A.; Cobo, Ramón; Martín-Cruces, José; García-Piqueras, Jorge; Feito, Jorge; García-Suárez, Olivia; Vega, Jose Antonio (Blackwell Publishing Ltd, 2020-09-29)
      The clitoris is a leading player in female sexual arousal, if not the main protagonist. Despite this role, studies performed on this structure with specific neuroanatomical techniques are few. This study focuses on glans ...
    • Article

      Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament (2024) 

      Gaite, Juan J.; Solé-Magdalena, Antonio; García-Mesa, Yolanda; Cuendias, Patricia; Martin-Cruces, José; García-Suárez, Olivia; Cobo, Teresa; Vega, José A.; Martín-Biedma, Benjamín (John Wiley and Sons Inc, 2023)
      PIEZO1 and PIEZO2 are essential components of mechanogated ion channels, which are required for mechanotransduction and biological processes associated with mechanical stimuli. There is evidence for the presence of PIEZO1 ...
    • Article

      Merkel Cell Carcinoma Display PIEZO2 Immunoreactivity (2024) 

      García-Mesa, Yolanda; Martín-Sanz, Raquel; García-Piqueras, Jorge; Cobo, Ramón; Muñoz-Bravo, Saray; García-Suárez, Olivia; Martín-Biedma, Benjamín; Vega, José Antonio; Feito, Jorge (MDPI, 2022)
      As an essential component of mechano-gated ion channels, critically required for mecha-notransduction in mammalian cells, PIEZO2 is known to be characteristically expressed by Merkel cells in human skin. Here, we ...
    • Article

      Sensory innervation of the human male prepuce: Meissner's corpuscles predominate (2021) 

      García-Mesa, Yolanda; García-Piqueras, Jorge; Cobo, Ramón; Martín-Cruces, José; Suazo, Iván; García-Suárez, Olivia; Feito, Jorge; Vega, Jose Antonio (Blackwell Publishing Ltd, 2021)
      Meissner's corpuscles are the most abundant sensory corpuscles in the glabrous skin of the male prepuce. They are type I, rapidly adapting, low-threshold mechanoreceptors, and their function is linked to the expression of ...
    • Article

      Sensory innervation of the human palmar aponeurosis in healthy individuals and patients with palmar fibromatosis (2024) 

      García-Martínez, Irene; García-Mesa, Yolanda; García-Piqueras, Jorge; Martínez-Pubil, Antonio; Cobo, Juan L.; Feito, Jorge; García-Suárez, Olivia; Vega, José A. (John Wiley and Sons Inc, 2022)
      The human palmar aponeurosis is involved in hand proprioception, and it contains different sensory corpuscle morphotypes that serve this role. In palmar fibromatosis (classically referred to as Dupuytren's disease), the ...
    • Article

      Synaptophysin is a selective marker for axons in human cutaneous end organ complexes (2024) 

      García-Mesa, Yolanda; García-Piqueras, Jorge; Cuendias, Patricia; Cobo, Ramón; Martín-Cruces, José; Feito, Jorge; García-Suarez, Olivia; Biedma, Benjamín Martín; Vega, J.A. (Elsevier GmbH, 2022)
      Background: Small clear synaptic-like vesicles fill axon terminals of mechanoreceptors. Their functional significance is controversial and probably includes release of neurotransmitters from afferent axon terminals. ...
    • Article

      The acquisition of mechanoreceptive competence by human digital Merkel cells and sensory corpuscles during development: An immunohistochemical study of PIEZO2 (2022) 

      García-Mesa, Yolanda; Feito, Jorge; Cuendias, Patricia; García-Piqueras, Jorge; Germanà, Antonino; García-Suárez, Olivia; Martín-Biedma, Benjamín; Vega, José A. (Elsevier GmbH, 2022-08)
      Background: PIEZO2 is a transmembrane protein forming part of an ion channel required for mechanotransduction. In humans, PIEZO2 is present in axon terminals of adult Meissner and Pacinian corpuscles, as well as Merkel ...