Listar Producción Científica por autor "Ochoa, Rodrigo"
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Article
Application of ensemble pharmacophore-based virtual screening to the discovery of novel antimitotic tubulin inhibitors (2021)
Gallego-Yerga, Laura; Ochoa, Rodrigo; Lans, Isaias; Peña-Varas, Carlos; Alegría-Arcos, Melissa; Cossio, Pilar; Ramírez, David; Peláez-Lamamié De Clairac, Rafael (Elsevier B.V., 2021-01)Tubulin is a well-validated target for herbicides, fungicides, anti-parasitic, and anti-tumor drugs. Many of the non-cancer tubulin drugs bind to its colchicine site but no colchicine-site anticancer drug is available. The ...