Listar Producción Científica por autor "García-Piqueras, Jorge"

Mostrando ítems 1-10 de 10

    • Article

      Glans clitoris innervation: PIEZO2 and sexual mechanosensitivity (2020) 

      García-Mesa, Yolanda; Cárcaba, Lucía; Coronado, César A.; Cobo, Ramón; Martín-Cruces, José; García-Piqueras, Jorge; Feito, Jorge; García-Suárez, Olivia; Vega, Jose Antonio (Blackwell Publishing Ltd, 2020-09-29)
      The clitoris is a leading player in female sexual arousal, if not the main protagonist. Despite this role, studies performed on this structure with specific neuroanatomical techniques are few. This study focuses on glans ...
    • Article

      Human digital merkel cells display pannexin1 immunoreactivity (2021) 

      Cárcaba, Lucía; García-Piqueras, Jorge; García-Mesa, Yolanda; Cobo, Ramón; García-Suárez, Olivia; Feito, Jorge; Vega, Jose Antonio (Elsevier GmbH, 2022-01)
      Pannexins are channel proteins displaying functional similarities to gap junctions in vertebrates and are regarded as transmembrane ATP-releasing channels. A member of this family, denominate pannexin1, has been detected ...
    • Article

      Immunohistochemical detection of PIEZO1 and PIEZO2 in human digital Meissner´s corpuscles (2024) 

      García-Mesa, Yolanda; Cuendias, Patricia; Alonso-Guervós, Marta; García-Piqueras, Jorge; Martín-Biedma, Benjamín; Cobo, Teresa; García-Suárez, Olivia; Vega, José A. (Elsevier GmbH, 2024)
      Background: The cutaneous end organ complexes or cutaneous sensory corpuscles are specialized sensory organs associated to low-threshold mechanoreceptors. Mechano-gated proteins forming a part of ion channels have been ...
    • Article

      Merkel Cell Carcinoma Display PIEZO2 Immunoreactivity (2024) 

      García-Mesa, Yolanda; Martín-Sanz, Raquel; García-Piqueras, Jorge; Cobo, Ramón; Muñoz-Bravo, Saray; García-Suárez, Olivia; Martín-Biedma, Benjamín; Vega, José Antonio; Feito, Jorge (MDPI, 2022)
      As an essential component of mechano-gated ion channels, critically required for mecha-notransduction in mammalian cells, PIEZO2 is known to be characteristically expressed by Merkel cells in human skin. Here, we ...
    • Article

      Peripheral mechanobiology of touch—studies on vertebrate cutaneous sensory corpuscles (2020) 

      Cobo, Ramón; García-Piqueras, Jorge; García-Mesa, Yolanda; Feito, Jorge; García-Suárez, Olivia; Vega, Jose A (MDPI AG, 2020-08-27)
      The vertebrate skin contains sensory corpuscles that are receptors for different qualities of mechanosensitivity like light brush, touch, pressure, stretch or vibration. These specialized sensory organs are linked anatomically ...
    • Article

      Sensory innervation of the human male prepuce: Meissner's corpuscles predominate (2021) 

      García-Mesa, Yolanda; García-Piqueras, Jorge; Cobo, Ramón; Martín-Cruces, José; Suazo, Iván; García-Suárez, Olivia; Feito, Jorge; Vega, Jose Antonio (Blackwell Publishing Ltd, 2021)
      Meissner's corpuscles are the most abundant sensory corpuscles in the glabrous skin of the male prepuce. They are type I, rapidly adapting, low-threshold mechanoreceptors, and their function is linked to the expression of ...
    • Article

      Sensory innervation of the human palmar aponeurosis in healthy individuals and patients with palmar fibromatosis (2024) 

      García-Martínez, Irene; García-Mesa, Yolanda; García-Piqueras, Jorge; Martínez-Pubil, Antonio; Cobo, Juan L.; Feito, Jorge; García-Suárez, Olivia; Vega, José A. (John Wiley and Sons Inc, 2022)
      The human palmar aponeurosis is involved in hand proprioception, and it contains different sensory corpuscle morphotypes that serve this role. In palmar fibromatosis (classically referred to as Dupuytren's disease), the ...
    • Article

      Synaptophysin is a selective marker for axons in human cutaneous end organ complexes (2024) 

      García-Mesa, Yolanda; García-Piqueras, Jorge; Cuendias, Patricia; Cobo, Ramón; Martín-Cruces, José; Feito, Jorge; García-Suarez, Olivia; Biedma, Benjamín Martín; Vega, J.A. (Elsevier GmbH, 2022)
      Background: Small clear synaptic-like vesicles fill axon terminals of mechanoreceptors. Their functional significance is controversial and probably includes release of neurotransmitters from afferent axon terminals. ...
    • Article

      The acquisition of mechanoreceptive competence by human digital Merkel cells and sensory corpuscles during development: An immunohistochemical study of PIEZO2 (2022) 

      García-Mesa, Yolanda; Feito, Jorge; Cuendias, Patricia; García-Piqueras, Jorge; Germanà, Antonino; García-Suárez, Olivia; Martín-Biedma, Benjamín; Vega, José A. (Elsevier GmbH, 2022-08)
      Background: PIEZO2 is a transmembrane protein forming part of an ion channel required for mechanotransduction. In humans, PIEZO2 is present in axon terminals of adult Meissner and Pacinian corpuscles, as well as Merkel ...
    • Article

      The Lamellar Cells of Vertebrate Meissner and Pacinian Corpuscles: Development, Characterization, and Functions (2024) 

      Suazo, Iván; Vega, José A.; García-Mesa, Yolanda; García-Piqueras, Jorge; García-Suárez, Olivia; Cobo, Teresa (Frontiers Media S.A., 2022)
      Sensory corpuscles, or cutaneous end-organ complexes, are complex structures localized at the periphery of Aβ-axon terminals from primary sensory neurons that primarily work as low-threshold mechanoreceptors. Structurally, ...