Association Between Arterial Stiffness and Blood Pressure Progression With Incident Hypertension: A Systematic Review and Meta-Analysis
Autor
Saz-Lara, Alicia
Bruno, Rosa María
Cavero-Redondo, Iván
Álvarez-Bueno, Celia
Notario-Pacheco, Blanca
Martínez-Vizcaíno, Vicente
Resumen
Background: Arterial stiffness is an independent predictor of cardiovascular and all-cause mortality that is classically regarded as a consequence of arterial hypertension. However, a growing number of studies have shown that arterial stiffness is involved in the pathogenesis and prognosis of arterial hypertension. Thus, in this systematic review and meta-analysis, we aimed to assess whether arterial stiffness, as measured by pulse wave velocity, systolic blood pressure and diastolic blood pressure are associated with incident hypertension. Methods: The Scopus, PubMed, Web of Science and Cochrane Library databases were searched from inception to March 30, 2021. The DerSimonian and Laird method was used to compute pooled relative risk estimates and their respective 95% confidence intervals of association between incident hypertension with pulse wave velocity, systolic blood pressure and diastolic blood pressure. Results: Our findings provide a synthesis of the evidence supporting that the higher arterial stiffness (RR: 1.09; 95% CIs: 1.05, 1.12), systolic blood pressure (RR: 1.08; 95% CIs: 1.05, 1.10) and diastolic blood pressure (RR: 1.08; 95% CIs: 1.04, 1.12) are associated with incident hypertension in normotensive adult subjects, with similar independent predictive values. However, our results should be interpreted with caution because the meta-analyses performed showed considerable heterogeneity. Conclusions: Our results showed that higher pulse wave velocity, systolic blood pressure and diastolic blood pressure are associated with incident hypertension. These findings are of clinical importance, supporting arterial stiffness as an additional tool for the prevention of arterial hypertension and being a fundamental component to reduce cardiovascular morbidity and mortality. Systematic Review Registration: This study was registered in PROSPERO https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=236435 (Registration number: CRD42021236435). Copyright © 2022 Saz-Lara, Bruno, Cavero-Redondo, Álvarez-Bueno, Notario-Pacheco and Martínez-Vizcaíno.
Colecciones
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Other
Corrigendum: Association Between Arterial Stiffness and Blood Pressure Progression With Incident Hypertension: A Systematic Review and Meta-Analysis(Front. Cardiovasc. Med., (2022), 9, (798934), 10.3389/fcvm.2022.798934) (2024)
Saz-Lara, Alicia; Bruno, Rosa María; Cavero-Redondo, Iván; Álvarez-Bueno, Celia; Notario-Pacheco, Blanca; Martínez-Vizcaíno, Vicente (Frontiers Media S.A., 2022)In the original article, we neglected to include the funder: “This article is partly based upon work from COST Action CA18216 VascAgeNet, supported by COST (European Cooperation in Science and Technology, http://www.cost.eu).” ... -
Article
Are advanced glycation end products in skin associated with vascular dysfunction markers? A meta-analysis (2020)
Saz-Lara, Alicia; Álvarez-Bueno, Celia; Solera-Martínez, Montserrat; Notario-Pacheco, Blanca; Sequí-Dominguez, Irene; Cavero-Redondo, Iván (MDPI AG, 2020-09-02)Evidence exists regarding the association between advanced glycation end products and different cardiovascular disease subclinical processes, such as arterial stiffness and atherosclerosis. With this systematic review and ... -
Article
Intima Media Thickness and Cognitive Function Among Adults: Meta-Analysis of Observational and Longitudinal Studies (2024)
Álvarez-Bueno, Celia; Cavero-Redondo, Iván; Bruno, Rosa Maria; Saz-Lara, Alicia; Sequí-Dominguez, Irene; Notario-Pacheco, Blanca; Martinez-Vizcaino, Vicente (American Heart Association Inc., 2022)BACKGROUND: Carotid structural changes measured by intima media thickness (IMT) have been related to cognitive complaints during aging. Therefore, the aims of this meta-analysis were (1) to elucidate the relationship between ...