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Frailty Index as a Predictor of Mortality in Middle-Aged and Older People: A Prospective Analysis of Chilean Adults
dc.contributor.author | Diaz-Toro, Felipe | |
dc.contributor.author | Nazar, Gabriela | |
dc.contributor.author | Troncoso, Claudia | |
dc.contributor.author | Concha-Cisternas, Yeny | |
dc.contributor.author | Leiva-Ordoñez, Ana Maria | |
dc.contributor.author | Martinez-Sanguinetti, Maria Adela | |
dc.contributor.author | Parra-Soto, Solange | |
dc.contributor.author | Lasserre-Laso, Nicole | |
dc.contributor.author | Cigarroa, Igor | |
dc.contributor.author | Mardones, Lorena | |
dc.contributor.author | Vásquez-Gómez, Jaime | |
dc.contributor.author | Petermann-Rocha, Fanny | |
dc.date.accessioned | 2023-02-21T15:07:39Z | |
dc.date.available | 2023-02-21T15:07:39Z | |
dc.date.issued | 2023-01 | |
dc.identifier | 10.3390/ijerph20021195 | |
dc.identifier.issn | 16617827 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12728/10229 | |
dc.description.abstract | We aimed to investigate the association between frailty status and all-cause mortality in middle-aged and older people. We included 2661 individuals aged ≥ 35 from the Chilean National Health Survey 2009–2010. Mortality was determined through linkage with the Chilean Civil Registry and Identification. A 36-item frailty index (FI) was used to assess the frailty status. Associations between frailty status and all-cause mortality were assessed using Kaplan–Meier and Cox proportional hazard models adjusted for sociodemographic and lifestyle factors. A non-linear association was investigated using penalized cubic splines fitted in the Cox models. During an 8.9 median follow-up (interquartile range of 8.6–9.0), 308 individuals died (11.5%). Lower survival rates were observed in frail individuals compared to pre-frail and robust people (log-rank < 0.001). Compared with robust individuals, frail people had a higher mortality risk (HR: 2.35 [95% CI: 1.57 to 3.51]). Frail middle-aged individuals had a higher risk of dying independently of major risk factors. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | MDPI | es_ES |
dc.subject | Chile | es_ES |
dc.subject | frailty | es_ES |
dc.subject | middle-aged | es_ES |
dc.subject | mortality | es_ES |
dc.title | Frailty Index as a Predictor of Mortality in Middle-Aged and Older People: A Prospective Analysis of Chilean Adults | es_ES |
dc.type | Article | es_ES |